China (Mainland)
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Esomeprazole magnesium (Trihydrate) china manufacture 99.0%min CAS NO.161973-10-0
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Product Details
Keywords
- Esomeprazole magnesium (Trihydrate)
- Esomeprazole magnesium
- Esomeprazole magnesium
Quick Details
- ProName: Esomeprazole magnesium (Trihydrate) c...
- CasNo: 161973-10-0
- Molecular Formula: 2(C17H18N3O3S)2.Mg
- Appearance: An Off White powder
- Application: used for medicine
- PackAge: Packaging according to customer requir...
- Port: china port
- ProductionCapacity: Metric Ton/Day
- Purity: ≥99.0%
- Storage: Room temperature preservation
- Transportation: by sea by air express
- LimitNum: 1 Kilogram
Superiority
usp standard
Details
|
Description |
White to slightly colored powder |
|
Solubility |
Soluble in methanol, slightly soluble in water, practically soluble in heptane |
|
Identification by a) IR b) AAS |
Sample spectrum /Absorption should match with standard |
|
Colour of Solution at 440 nm (2.0 % w/v solution in methanol) |
NMT 0.2 |
|
Specific Rotation at 20 ℃(1.0% w/v solution in methanol)( On Anhydrous basis） |
NLT –137.0 °~ –142.0° |
|
Water (%w/w) |
6.0% to 8.0 % |
|
Chromatographic Purity by HPLC (%)
|
a) N-Oxide Analogue. NMT 0.1% b) Sulfone Analogue NMT 0.2% c) Benzimidazole Analogue NMT 0.1% d) Dis-methoxy Analogue NMT 0.1% e) Sulphide Analogue NMT 0.1% f) Any other Individual Impurity NMT 0.1% g) Total Impurities NMT 0.5% |
|
Enantiomeric Purity (%)
|
a) Purity NLT 99.8% b) R-Omeprazole NMT 0.2% |
|
Magnesium Content ( % w/w) (On Anhydrous Basis） |
3.30% to 3.55% |
|
Assay by HPLC (% w/w) (On Anhydrous Basis) |
98.0 % to 102.0% |
|
Residual Solvents by GC-HS (ppm)
|
a) Methylene Chloride NMT 600ppm b) Methanol NMT 3000ppm c) Acetone NMT 5000ppm d) Ethyl Acetate NMT 5000ppm
|
e) Toluene NMT 900ppm|
Description |
White to slightly colored powder |
|
Solubility |
Soluble in methanol, slightly soluble in water, practically soluble in heptane |
|
Identification by a) IR b) AAS |
Sample spectrum /Absorption should match with standard |
|
Colour of Solution at 440 nm (2.0 % w/v solution in methanol) |
NMT 0.2 |
|
Specific Rotation at 20 ℃(1.0% w/v solution in methanol)( On Anhydrous basis） |
NLT –137.0 °~ –142.0° |
|
Water (%w/w) |
6.0% to 8.0 % |
|
Chromatographic Purity by HPLC (%)
|
a) N-Oxide Analogue. NMT 0.1% b) Sulfone Analogue NMT 0.2% c) Benzimidazole Analogue NMT 0.1% d) Dis-methoxy Analogue NMT 0.1% e) Sulphide Analogue NMT 0.1% f) Any other Individual Impurity NMT 0.1% g) Total Impurities NMT 0.5% |
|
Enantiomeric Purity (%)
|
a) Purity NLT 99.8% b) R-Omeprazole NMT 0.2% |
|
Magnesium Content ( % w/w) (On Anhydrous Basis） |
3.30% to 3.55% |
|
Assay by HPLC (% w/w) (On Anhydrous Basis) |
98.0 % to 102.0% |
|
Residual Solvents by GC-HS (ppm)
|
a) Methylene Chloride NMT 600ppm b) Methanol NMT 3000ppm c) Acetone NMT 5000ppm d) Ethyl Acetate NMT 5000ppm
|