Zidovudine CAS NO.30516-87-1

Appearance: White to yellowish powder Specific rotation :+60.5°~ +63.0° Solubility Sparingly :soluble in water,soluble in alcoho…

 Appearance: White to yellowish powder 

Specific rotation :+60.5°~ +63.0° 

Solubility Sparingly :soluble in water,soluble in alcohol. 

Melting point: About 125℃ 

Identification:

A:IR absorption spectrum:

Corresponds to the IR spectrum of Zidovudine

RS

B: HPLC

Corresponds to the retention time of major

peak in the chromatogram of the standard preparation.

Water: ≤1.0% 

Residue on ignition :≤0.25% 

Test A (TLC):Sum of all impurities ≤3.0% 

Test B(HPLC):Zidovudine related compound B :≤1.0% 

Zidovudine related compound C :≤2.0% 

Sum of all impurities(A+B) :≤3.0% 

Tapped density :0.55~0.7g/ml 

Bulk density :<0.45g/ml 

Residual solvents:

Methanol: ≤0.2%

Triethylamine: ≤0.02%

Ethyl acetate:≤0.2%

Dioxane:≤0.02%